Related Party Transactions and Outside Related Director Information

Regeneron Pharmaceuticals, Inc. (REGN)

4/21/2006 Proxy Information

No related party transactions or special transactions reported for this company. Director relationships marked "Outside Related" at this firm will most often be former executives of the company. Additional information regarding these relationships will be added during our regular updates.

4/29/2005 Proxy Information

In 1994, the Company made a $60,000 loan to Dr. Yancopoulos who was then our Vice President, Discovery and is now our Executive Vice President, Chief Scientific Officer, President, Regeneron Research Laboratories, and a director. The loan was repaid in full on its maturity date in August 2004. Since January 1, 2004, the largest aggregate indebtedness under the loan (principal and interest at the rate of 6.83% per year) was $100,878.

4/23/2004 Proxy Information

In August 1994, the Company loaned Dr. Yancopoulos $60,000. The loan is evidenced by a promissory note bearing interest at the rate of 6.83% per year. The loan, including all accrued interest, totaled $99,461 as of April 16, 2004, and becomes due and payable on August 21, 2004, unless Dr. YancopoulosŐs employment with the Company terminates prior to that date.

On December 31, 1998, Dr. Vagelos entered into an employment agreement with Regeneron Pharmaceuticals, Inc., pursuant to which, effective January 1, 1999, he became a part-time employee.

Mr. Shooter is a co-founder of Regeneron Pharmaceuticals, Inc.

5/1/2003 Proxy Information

Dr. Alfred Gilman a co-founder of Regeneron Pharmaceuticals, has been a member of the Scientific Advisory Board since 1988.

Dr. Eric Shooter a co-founder and director of Regeneron Pharmaceuticals, Inc.

Roy Vagelos has been Chairman of Regeneron Pharmaceuticals, Inc. and a member of the scientific advisory board since January 1995. He became a part-time employee of Regeneron in January 1999.